The Effect of SudanⅠon Exressions of CYP 2E1

摘要：

　　The protein and mRNA of CYP 2E1 are detected by Immunohistochemistry (IHC)and in situ hybridization (ISH).The experiment is to observe the effect of SudanⅠ on expression of CYP 2E1 and hepatic injury.Experimental animals are randomly divided into control group (C group)and Sudan Ⅰ treatment group.The results of IHC examination show that IOD of CYP 2EI protein has increase (P<0.01 )in livers in Sudan Ⅰ treatment groups and show uptrend in certain dose range.The results of ISH examination show that IOD of CYP 2ElmRNA is significant increase (P<0.01 )in livers in SudanⅠtreatment groups and show uptrend in certain dose range.The results indicate that SudanⅠ can induce increase of the expressions of CYP 2E1.

作者: Li Xiangfeng Zang Yating Lu Qin Cui Yanyan Niu Xin Xie Lijun Wang Weina Wang Xia Sun Wenhui Gao Hong Zhao Ru Yan Yulin Jiang Huan Chen Gang Huang Hui Shao Zhiyong

作者单位: College of Animal Science & Technology,Yunnan Agricultural University,Kunming 650201,China

会议类型: 国际会议

会议名称: XVIth International Congress on Animal Hygiene(第十六届动物卫生国际会议(ISAH 2013))

会议地点: 南京

会议语种:英文

页码: 498-500

在线出版日期: 2013-05-05（万方平台首次上网日期，不代表论文的发表时间）