Experimental Studies on Toxic Interaction of Oxytetracycline and Cadmium

摘要：

　　These experimental studies were carried out on 450 Ross chicks divided into 6 groups.Some of these groups administered a therapeutic dose of oxytetracycline(OTC)plus cadmium(0.1 ppm cadmium chloride in drinking water),other groups were given over concentration of OTC (6g/l of drinking water),double the therapeutic dose plus the same dose of cadmium chloride.It had been reported that administration of OTC,OTC plus cadmium had a serious effect on both the muscular tissue and the parynchymatous organs including hepatocellular degeneration,focal lymphoid cell reaction and fibroblastic reaction in the portal area of liver,nephrosis of kidney with degeneration of some renal tubules and depletion of lymphoid cells of white pulp of spleen.It was also associated with cellular immune suppression.So new laws regulating administration of antibiotic should be enforced.

关键词： oxytetracycline cadmium toxicity chicks

作者: Thabet A.Ibrahim Diefy A.Salem Ahmed A.Sharkawy Mahmoud A.Z Mohammed Abdelhadi

作者单位: Department of Forensic Med.and Toxicology,Fac.of Vet.Med.,Assiut University,Egypt Department of Pathology,Fac.of Vet.Med.,Assiut University,Egypt

会议类型: 国际会议

会议名称: XVIth International Congress on Animal Hygiene(第十六届动物卫生国际会议(ISAH 2013))

会议地点: 南京

会议语种:英文

页码: 575-577

在线出版日期: 2013-05-05（万方平台首次上网日期，不代表论文的发表时间）