Preparation, Characteristics and Bioactivity of Gypenosides -Loaded Microcapsules
Microencapsulation has great potential extensive applications in fields of cosmetics,pesticides,pharmaceutical and medical applications,foods,biology,catalysis,carbonless copying paper and many other areas.Gypenosides (GPS) are extracted from Gynostemma pentaphyllum Makino,widely used in Southeast Asian folk medicine or food.In the current study,Gypenosides-loaded microcapsules (GPMC) were prepared by gelatin/gum.Characteristics and bioactivity of the GPMC were evaluated.An up to 80% encapsulation of GPS at pH 4.0 was achieved,with 1∶2 drug to wall materials ratio and a 3% gelatin/gum arabic while stirring at 500 r/min.Microscopy revealed an average microcapsule size of 52.4 μm.Pharmacological studies showed that GPMC exhibited excellent therapeutic effects,such as expectorant activity,cough relieving and anti-inflammatory effect.The results indicate that microcapsulation is a safe and efficient delivery for GPS.
Microencapsulation Preparation Microcapsules Gypenosides
Fan Yu
1Dr.Fan Yu, Yancheng Teachers University, Yancheng, P.R.China
国际会议
太原
英文
329-332
2013-03-22（万方平台首次上网日期，不代表论文的发表时间）