A new metabolic pathway of heptachlor epoxide biotransformation by Cordyceps brongniartii ATCC66779
Although heptachlor epoxide (HE) is the major metabolite of organochlorine pesticide heptachlor in soil, there is very limited information on the biodegradation of HE by microorganisms,and no systematic study on the metabolic products and pathways for HE transformation by fungi has been conducted.In this study, the metabolism of HE was performed with Cordyceps brongniartii ATCC66779, which is capable of degrading polychlorinated dibenzo-p-dioxin.This fungus removed about 27% and 21% of HE in PDB and B SM medium, respectively, after 20 days of incubation.Three hydroxylated products including heptachlor diol, 1,2-dihydroxydihydrochlordene and trihydroxychlordene were detected as metabolites of HE using GC/MS analysis, suggesting that HE was metabolized to hydrophilic products via hydrolysis, dechlorination and hydroxylation.
heptachlor epoxide Cordyceps brongniartii ATCC66779 metabolic pathway hydrolysis dechlorination hydroxylation
Pengfei Xiao Yuzhen Song
College of Forestry, Northeast Forestry University, Harbin, China
国际会议
杭州
英文
295-298
2013-01-18（万方平台首次上网日期，不代表论文的发表时间）