Screening of a Mortierella isabellina mutant for producing arachidonic acid
Arachidonic acid (AA) is an essential component of structural lipids in the cellular membranes of mammals.To obtain efficient AA-producing microorganism,the strain of Mortierella isabellina 3410 was subject to mutagenesis by treating the wild-type spores exposed to ultraviolet or diethyl sulfate.A mutant of M.isabellina MS-1 was screened and chosen because of its higher AA production capability.Compared with the wild strain of M.isabellina 3410,the AA production by mutant of M.isabellina MS-1 was increased about 2.5 folds.Analysis by gas chromatography (GC) indicated that AA was the main fatty acid in the lipids extracted from the dried mycelia of the mutant of M.isabellina MS-1.
arachidonic acid Mortierella isabellina mutant screening
Ming Chen Chunzhi Zhang Yongpeng Yu Guoren Zu Li Chen
College of Bioengineering, Dalian Polytechnic University, Dalian 116034, P.R.China
国际会议
厦门
英文
793-796
2012-12-28（万方平台首次上网日期，不代表论文的发表时间）