Mechanical and Biological characteristics of electrospun PCL meshes--the influence of solvent type and concentration
Non-woven scaffolds,with fiber dimensions at a nanometer scale,can mimic the physical structure of natural extracellular matrices,being ideal construts for Tissue Engineering applications.This research work explores solution electrospinning to produce nanoscale meshes.Different Poly (ε-caprolactone) (PCL) solutions were considered and the influence of both polymer concentration and type of solvent studied regarding the fabrication of polymeric meshes and their mechanical and biological properties.PCL solutions were prepared using two different solvents:glacial acetic acid with triethylamine (AA/TEA)) and Acetone (DMK) at different concentrations.PCL/AA/TEA meshes present better mechanical properties and good cell viability and proliferation.
Electrospinning Nanofibers Polycaprolacone Tissue Engineering
Dias Juliana Gloria Antonio Bártolo Paulo
Centre for Rapid and Sustainable Product Development, Polytechnic Institute of Leiria, Marinha Grand Institute of Composite and Biomedical Materials-Research Council-P.le Tecchio 80, 80125-Naples, Ital
国际会议
北京
英文
137-140
2012-12-16（万方平台首次上网日期，不代表论文的发表时间）