CONSTRUCTION OF AN INTEGRATED ELECTROCARDIOGRAM DATABASE FOR SURVEILLANCE OF DRUG-INDUCED QT PROLONGATION

摘要：

　　Using electrocardiogram (ECG) parameters from a number of ECG data sources, an ECG database was constructed for surveillance of QT interval prolongation induced by marketed drugs. The ECG data were collected from three hospital data sources: scanned ECG printouts, an ECG management system, and an electronic health records system. In total, 0.7 million blinded ECG records were captured from 0.4 million individual patients. Optical character recognition (OCR) and Web-parsing techniques were used to extract the ECG parameters. By using OCR and Web parsing, a significant number of ECG records from daily practice could be successfully transferred into an ECG database.

关键词： Adverse drug event post marketing surveillance pharmacovigilance QTc prolongation

作者: Man Young Park Dukyong Yoon Ehn Kyoung Ahn Woojae Kim Rae Woong Park

作者单位: Department of Biomedical Informatics, Ajou University School of Medicine, Suwon, South Korea

会议类型: 国际会议

会议名称: The 7th Asia Pacific Association for Medical Informatics Conference(第七届亚太医药信息学大会(APAMI2012))

会议地点: 北京

会议语种:英文

页码: 1-2

在线出版日期: 2012-10-24（万方平台首次上网日期，不代表论文的发表时间）