Preparation of Simvastatin Loaded TiO2 nanotube arrays and its release behavior

摘要：

　　TiO2 nanotube array fabricated by anodization has large specific surface area and good biocompatibility.The simvastatin (SIM),which can promote bone formation,were filled into the TiO2 nanotube by using step concentration soaking method(SCS).The morphology of TiO2 nanotube arrays were observed by scanning electronic microscope,and the drug release in phosphate buffer solution (PBS) were determined by visible ultraviolet spectrophotometer.The results show that the simvatatin has been loaded into the TiO2 nanotube arrays,and could sustain release 15 days.

关键词： TiO2 nanotube array simvastatin release

作者: Haizhen Tang Xiufeng Xiao Yirong Chen Rongfang Liu

作者单位: College of Chemistry and Chemical Engineering,Fujian Normal University,Fuzhou,Fujian,China

会议类型: 国际会议

会议名称: the 2nd International Conference on Electronic & Mechanical Engineering and Information Technology (EMEIT-2012)(2012年电机工程与信息技术国际会议)

会议地点: 沈阳

会议语种:英文

页码: 1138-1141

在线出版日期: 2012-09-26（万方平台首次上网日期，不代表论文的发表时间）