Comparison of Toxicity Induced by Single-Wall and Multi-Wall Carbon Nanotubes by Using of Plasmid DNA Assay

摘要：

　　Bioreactivity of single-walled carbon nanotubes (SWNTs) and multi-walled carbon nanotubes (MWNTs) was assessed by using of plasmid DNA assay and morphological variation of neural stem cells.The results of plasmid DNA assay showed that 48.5% and 21.1% of supercoiled DNA damage caused by SWNTs and MWNTs respectively at the same concentration.Cellular activity results testified that cytotoxicity of SWNTs was stronger than that of MWNTs.The different bioreactivity of the two kinds of nanocarbontubes might caused by the higher mass level of heavy elements embodied in the SWNCTs.

关键词： Single-walled carbon nanotubes (SWNTs) multi-walled carbon nanotubes (MWNTs) bioreacitvity plasmid DNA, heavy metals

作者: Senlin LU Jingjing REN Fei YI Xiaojie HAO Shinich YONEMOCHI Xiaoju WANG

作者单位: School of Environmental Sciences and Chemical Engineering Shanghai University Shanghai 200444,China Center for Environmental Science in Saitama,Saitama 374-0115,Japan

会议类型: 国际会议

会议名称: Conference on Environmental Pollution and Public Health (2012年环境污染与大众健康学术会议(CEPPH2012))

会议地点: 上海

会议语种:英文

页码: 131-133

在线出版日期: 2012-08-09（万方平台首次上网日期，不代表论文的发表时间）