Study on Metabolites and Mutation of Benzokfluoranthene by Peroxynitrite/Fe(Ⅲ)porphyrin Biomimetic System

摘要：

　　The metabolites of benzokfluoranthene under the peroxynitrite /T(p-Cl)PPFeCl (peroxynitrite/(chloride)iron(Ⅲ)tetrakis (p-chlorophenyl)porphyrin) system have been identified with HPLC-MS.The results showed that benzokfluoranthene was activated to form two new metabolites induced by PN/pClFeTPPCl system,which were OH group,and nitro group.In the Ames test,admixture of benzokfluoranthene metabolites showed significantly high mutagenicity while benzokfluoranthene parent did not show positive result during the test.

关键词： PAHs benzokfluoranthene PN/p-ClFeTPPCl Ames test

作者: Shaohui Li Yunjing Luo Shufen Zhang Yuanbin She Rugang Zhong

作者单位: College of Life Science and Bioengineering,Beijing University of Technology,Beijing,100124,China College of Environmental and Energy Engineering,Beijing University of Technology,Beijing,100124,Chin

会议类型: 国际会议

会议名称: Conference on Environmental Pollution and Public Health (2012年环境污染与大众健康学术会议(CEPPH2012))

会议地点: 上海

会议语种:英文

页码: 705-708

在线出版日期: 2012-08-09（万方平台首次上网日期，不代表论文的发表时间）