Ceramics and metallic material are commonly used in biomedical filed.Ceramic material,such as hydroxyapatite (HAP),is bioresorbable and has osteoconduction and osteoinduction.Metallic material,such as stainless steel (SS),possesses good mechanical properties and chemical stability.Thus,the study aim was combination of the two together can form the bone scaffold applied in bone tissue engineering,providing desirable support,cell growth,and cell attachment for bone tissue.This study method is braid the SS filaments into a three-dimensional structure of braid.By electrochemical technique,HAP is then coated on the braid,forming the three-dimensional HAP/SS bone scaffold.Simulated body fluid,the electrolyte solution,is heated into various temperatures to simulate the environment,and the current supplied in the electrochemical technique remains constant.A scanning electron microscope (SEM) observes the surface of the scaffold,and energy dispersive spectrometer (EDS) further evaluates the HAP attachment in terms of calcium-phosphorus (Ca/P) ratio,determining the optimal Ca/P ratio that is similar to that of human bone tissues to accelerate recovery of bone tissues.The result shows three-dimensional HAP/SS bone scaffolds are covered with HAP particles.
hydroxyapatite stainless steel calcium-phosphorus
Ching-Wen Lou Yueh-Shencl Chen Ching-Wen Lin Chien-Lin Huang Wen-Cheng Chen Jia-Horng Lin
nstitute of Biomedical Engineering and Material Science, Central Taiwan University of Science and Te Department of Biomedical Imaging and Radiological Science, China Medical University, Taichung 40402, Department of Fashion Design, Asia University, Taichung 41354, Taiwan, R.O.C. Feng Chia University, Taichung City 407, Taiwan, R.O.C. Advanced Medical Devices and Composite Laboratory, Department of Fiber and Composite Materials, Feng Laboratory of Fiber Application and Manufacturing, Department of Fiber and Composite Materials,Feng