Film Properties of Poly(lactic acid) Comprising N-methyl-2-pyrrolidone
Poly (lactic acid) (PLA) has many potential uses,for example as packaging,textiles,biomedical fields,including suture,bone fixation material,drug delivery microsphere,and tissue engineering.However,PLA shows the poor toughness,slow degradation rate and relatively hydrophobic.The aim of this study was to investigate the ability of N-methyl-2-pyrrolidone (NMP) to improve the characteristics of PLA film.PLA films were prepared using a solvent casting method and their various properties were investigated.From tensile strength (TS),elongation at break (E) and youngs modulus(ε) determinations,the incorporated PLA films exhibited the softer behavior than plain PLA film.On the other hand,from the contact angle and surface free energy values,the PLA films incorporated with NMP could improve the wettability of solvents and also increased % water sorption (WS) and % weight loss (WL) than PLA films with NMP dose dependent.However SEM photographs revealed the more rather rough and cracked surface as the higher amount of NMP was incorporated in PLA film.
film properties PLA NMP
Sasiprapa Chitrattha Thawatchai Phaechamud
Department of Pharmaceutical Technology, Faculty of Pharmacy,Silpakorn University, Nahkon Pathom, 73000 Thailand
国际会议
香港
英文
140-143
2012-07-26（万方平台首次上网日期，不代表论文的发表时间）