Polymeric Eutectic System

摘要：

　　The liquid eutectic system comprising 1∶1 menthol:camphor was selected to use as solvent due to it was lowest viscosity.Both menthol and camphor used in this eutectic system have been reported for their many pharmaceutical used.Various polymers were tested for their solubility in this eutectic system.Eudragit(R) EPO showed the highest solubility.Eudragit(R) EPO was the one of biocompatible polymer which could dissolve in this eutectic system up to 40% w/w with no chemical interaction of each compound.Viscosity of this system showed the exponential curve as a function of polymer concentration but all concentration showed the newtonian rheology.The pH and surface tension were slightly affected by type and amount of polymers.The obtained polymeric eutectic mixture should control the drug release for pharmaceutical applications.

关键词： Eutectic mixture Menthol Camphor and Polymer

作者: S.Tuntarawongsa T.Phaechamud

作者单位: Department of Pharmaceutical Technology, Faculty of Pharmacy,Silpakorn University, Nakhon Pathom, 73000 Thailand

会议类型: 国际会议

会议名称: the 2012 International Conference on Frontiers of Nanoscience and Technology(2012年纳米科学与技术国际会议(ICFNST 2012))

会议地点: 香港

会议语种:英文

页码: 180-183

在线出版日期: 2012-07-26（万方平台首次上网日期，不代表论文的发表时间）