PH-sensitive nanoparticles of derivated dextran grafted with 1-(3-aminopropyl) imidazole
Dextran catches increasing attentions as a drug carrier because of its biocompatibility,biodegradability and ease of modification.In this study,we synthesized the derivated dextran by grafting with 1-(3-aminopropyl) imidazole.The dextran-based nanoparticles with sizes of < 200 nm were successfully prepared by nanoprecipitation,and its pH-sensitivities were investigated.The samples were fully characterized by FTIR,1H NMR,SEM,AFM and Zetasizer.
PH-sensitive Nanoprecipitation Self-assembly Dextran Nanoparticles
He Lei Guoliang Zhang
School of Chemical Engineering and Technology, Tianjin University
国际会议
太原
英文
131-136
2012-06-23(万方平台首次上网日期,不代表论文的发表时间)