Mechanical Properties of Poly (ε-caprolactone)/ Polyethylene Terephthalate Composite Prototype Small Diameter Vascular Graft

摘要：

　　The purpose of the vascular grafts or implantation is not only to keep a patient alive,but for the patient to continue with their normal lives.Polyethylene terephthalate (PET) has been successfully used in large diameter grafts; unfortunately,small diameter grafts were failures.Due to surface forces,blood plasma proteins are adsorbed by the graft,resulting vessel reclosure Poly (ε-caprolactone) (PCL) is a promising biodegradable polymer with a longer degradation time.The mechanical properties of the pure PCL membrane cannot meet the requirement.The aim of this study is to develop new vascular graft from PCL reinforced with PET monofilament weft-knitted tube fabric.The PET fabrics were knitted using small single jersey knitting machine.Then PCL solution was coated outside and inside of the weft-knitted fabric with a PTFE rod,and the pure PCL tube was taken as a control.The samples were dried by freeze drying method.The results have shown that the new vascular grafts have good porosity.In addition the tensile properties,elastic recovery and the suture retention strength of the new prototype vascular grafts were improved compared with pure PCL vascular graft,which could be used in clinical application.

关键词： Polyethylene terephthalate Monofilament Weft-knitted tube fabric Poly (ε-caprolactone) (PCL) Mechanical properties Vascular graft

作者: Mohammed Abedalwafa LI Chao-Jing WANG Fu-Jun WANG Lu LIAN Ming-qiang JIA Hao

作者单位: Key Laboratory of Textile Science and Technology, Ministry of Education, College of Textiles, Donghua University,Shanghai , China

会议类型: 国际会议

会议名称: 2012 International Forum on Biomedical Textile Materials (2012国际纺织生物医用材料论坛)

会议地点: 上海

会议语种:英文

页码: 132-137

在线出版日期: 2012-06-08（万方平台首次上网日期，不代表论文的发表时间）