Electrochemical Sensors for L-Tryptophan Based on Molecularly Imprinted Polymers
A novel sensing element for direct detection of L-Tryptophan (L-Trp) in human serum was proposed by combination of electrochemical transduction and molecular imprinting technique.The sensing element was prepared by electropolymerization of o-phenylenediamine (o-PD) on the gold electrode in the presence of template L-Trp.The electrochemical property of the sensor was characterized by differential pulse voltammetry (DPV).The linear response range of the sensor for L-Trp concentration was 1× 108 mol/L~21 × 10-8 mol/L with a detection limit of 0.3 × 108 mol/L.The results show that this approach has the potential to generate a universal inexpensive assay methodology of high sensitivity,specificity and simplicity to detect L-Trp.
Molecular imprinting Electropolymerization Electrochemical sensor L-Tryptophan o-Phenylenediamine
XU Wen LI Xiao ZHANG Weiying YING Xiaoguang
College of Chemistry and Chemical Engineering, Fuzhou University, Fuzhou 350108, China
国际会议
杭州
英文
434-438
2012-03-23(万方平台首次上网日期,不代表论文的发表时间)