INFLUENCE OF PROCESS PARAMETERS ON THE PARTICLE SURFACE STRUCTURE IN FLUIDIZED BED SPRAY GRANULATION
Fluidized bed spray granulation is an important process for the formulation of a solid from a liquid starting material.The property of the produced granule like particle structure is depending on the chosen process parameters.Especially in pharmaceutics and food industry specific standards were posed to the granule surface.Depending on the application,the granules should dissolve rapidly or release over a longer period of time the active ingredient.These require differently structured surfaces.As part of this work model substances were used to investigate the influence of different spraying rates and temperatures on the formation of granule surface structures.
fluidized beds particle surface structure spray granulation process
T.Hoffmann M.Peglow E.Tsotsas
NaWiTec,Thermal Process Engineering,Otto-von-Guericke University Magdeburg Universit(a)tsplatz 2,Magdeburg,D-39106,Germany
国际会议
The 18th International Drying Symposium Conference(第十八届国际干燥学术大会(IDS2012))
厦门
英文
1-6
2012-01-11(万方平台首次上网日期,不代表论文的发表时间)