A NOVEL ALGORITHM FOR GENERATING SIMULATED GENETIC DATA BASED ON K-MEDOIDS
Genetic data is very important for biological research,but it is hard to be obtained by experiment.In this paper,we introduce an algorithm for generating simulated genetic data based on K-mediods.A concept of Cluster Channel is proposed in this algorithm and used to generate simulated data.The noise of origin data could be eliminated using the proposed method.The experimental results show reliability of simulated genetic data.SAM is used to analyze the simulated data and original data,and we get a conclusion that the simulated data can effectively validate differentially expressed gene detected algorithm.
Genetic data Simulated genetic data K-medoids Cluster channel
Jianan Wu Chunguang Zhou Zhangxu Li Xuefei Xia Seng Zhang You Zhou
College of Computer Science and Technology,Jilin University,Changchun 130012,China;College of Comput College of Computer Science and Technology,Jilin University,Changchun 130012,China College of Jilin Communications Polytechnic,Changchun 130012,China College of Computer Science and Technology,Changchun University,Changchun 130012,China
国际会议
杭州
英文
29-32
2012-10-30(万方平台首次上网日期,不代表论文的发表时间)