Efficacy and Safety of Nasal Administration of Nano-L-DOPA based on PLGA nanoparticles

摘要：

　　Inclusion of L-DOPA,the standard Parkinsons disease medication,into polymeric particles (PLGA) results in optimization the drug metabolism and increasing its bioavailability,significantly increases of physical endurance,better coordination and lower anxiety in Wistar rats,when chronically administered nasally.

关键词： nanopaticls L-DOPA nasal administration Parkinsons disease

作者: I.G.Kondrasheva T.A.Antipova G.G.Barsegyan P.Ye.Gambaryan A.A.Guseva A.A.Kamensky

作者单位: Research Center of Molecular Diagnostics & Therapy Moscow, Russia Moscow State University Moscow, Russia

会议类型: 国际会议

会议名称: 2012世界工程和技术大会

会议地点: 北京

会议语种:英文

页码: 25-27

在线出版日期: 2012-10-26（万方平台首次上网日期，不代表论文的发表时间）