Networks of Nature-Family-Component of Chinese Medicine Herbs Based on Association Rules Mining
Objective:The aim of this study was to explore appropriate methods for the research of the theory of Chinese medicine nature property and find the relationship between Nature-Component of Chinese medicine herbs.Methods:From perspective of systems biology,we used Associate Network (AN) to identify useful relationships among Nature-Family-Component of Herbs.In this work,AN combines association rules mining method and network construction method to evaluate the complicate relationship among Nature-Family-Component of herbs screened.Result:The results of association rules mining showed that the families had close relationship with the nature properties of herbs.For example,the families of Magnoliaceae,Araceae have close relationship to hot nature with Confidence of 100%,the families of Cucurbitaceae has close relationship to cold nature with Confidence of 90.91%.Moreover,the results of constructed Associate Network implied that herbs belonging to the same families generally have the same natures.In addition,some herbs belonging to different families may also have same natures when they contain the same main components.Conclusion:These results implied that the main components of herbs affect their natures; the relationships between families and natures were based on the main compounds of herbs.
Associate Network Nature-Family-Component Chinese Medicinal Herbs
FU Xian-Jun WANG Zhen-Guo QU Yi WANG Peng Yu Hua-Yun
School of information management, Shandong University of Traditional Chinese Medicine, Jinan250355, School of information management, Shandong University of Traditional Chinese Medicine, Jinan250355, Eye Institute of Shandong University of Traditional Chinese Medicine, Jinan250002, China
国际会议
南京
英文
372-376
2012-05-13(万方平台首次上网日期,不代表论文的发表时间)