Preparation and Drug Release Properties of IBU-loaded Mesoporous Calcium Silicate Hydrate (CSH) spheres

摘要：

　　The novel kind flowerlike mesoporous spheres of calcium silicate hydrate (CaO·SiO2·H2O,CSH) have been synthesized by co-precipitation method on based with water/alcohol/calvital/tetraethyl orthosilicate (TEOS) system.The synthesized CSH were applied as a carrier to study the loaded behaviors of ibuprofen(IBU),was used to investigate the drug loading behavior of the CSH for different times has been also discussed.The drug loading capacities(DLCs) of CSH loaded for 12h has reached 116.78wt.%.The structural,morphological and textural properties were investigated by SEM,FTIR,TG and BET.The results show that it would be a good candidate as drug carrier for bone repair.

关键词： Calcium silicate hydrate Mesoporous drug carrier

作者: Ya Dong Huiwen Yuan Yaru Ni Chunhua Lu Zhongzi Xu

作者单位: State Key Laboratory of Materials-Orient Chemical Engineering, College of Materials Science and Engineering, Nanjing University of Technology,210009,Nanjing, P.R.China

会议类型: 国际会议

会议名称: the 2011 International Conference on Biotechnology, Chemical and Materials Engineering (2011生物,化学与材料工程国际会议(CBCME 2011))

会议地点: 昆明

会议语种:英文

页码: 894-897

在线出版日期: 2011-12-28（万方平台首次上网日期，不代表论文的发表时间）