The Binding Performance of Erythromycin Imprinted Polymeric Microspheres
Erythromycin molecularly imprinted polymeric microspheres (EM-MIPMs) which have good shape and well-distributed size were prepared by suspension polymerization in aqueous phase,using EM as a template and methacrylic acid (MAA) as a functional monomer.The size of MIPMs is about 50.17 μm characterized by laser particle size analyzer and polarizing microscope.The interaction between the template and monomer,and selective binding performance were investigated by ultraviolet spectrum analysis,equilibrium binding experiments and Scatchard analysis.The results show that hydrogen bonding may contribute to the interaction between EM and MAA,EM-MIPMs demonstrated much higher adsorption capacity compared with the NMIPMs.It has also been found that there are two kinds of binding sites in EM-MIPMs and only one kind in NMIPMs.
Erythromycin molecularly imprinted polymer microspheres binding
Ping Guan XiaoLing Hu Li Zhu
School of sciences,Northwestern Polytechnical University,Xian 710072,China;The Key Laboratory of Space Applied Physics and Chemistry,Ministry of Education,Xian,710072,China
国际会议
the Asian Workshop on Polymer Processing 2011(2011高分子加工技术亚洲研讨会(AWPP2011))
青岛
英文
263-268
2011-11-04（万方平台首次上网日期，不代表论文的发表时间）