Interactions Analysis in BSA-Ioaded Chitosan Nanoparticles at Different pH Values

摘要：

　　In this paper,the properties of chitosan nanoparticles and bovine serum albumin-loaded chitosan nanoparticles prepared with sodium tripolyphosphate at different pH values were discussed.Interactions in chitosan nanoparticles and bovine serum albumin-loaded chitosan nanoparticles were analyzed by Fourier transform infrared spectroscopy and differential scanning calorimetry.The results indicated that there were more complicated interactions in chitosan nanoparticles prepared at different pH values.When the pH values were lower or higher than isoelectric point value of target protein (bovine serum albumin),the big different interactions occurred in chitosan nanoparticles.These differences also would result in different releasing properties.

关键词： Chitosan Bovine Serum Albumin Nanoparticles Interaction

作者: Yong Liu Yan Sun Yanli Li Shaochun Xu Yaoxing Xu

作者单位: Institute of Plant Protection and Microbiology,Zhejiang Academy of Agricultural Sciences,198 Shiqiao Hangzhou Normal University,222 Wenyi Road,Hangzhou,Zhejiang Province,P.R.China

会议类型: 国际会议

会议名称: the international conference on Frontier of Nanoscience and Technology (2011纳米科学与技术国际会议(ICFNST 2011))

会议地点: 大理

会议语种:英文

页码: 160-164

在线出版日期: 2011-08-18（万方平台首次上网日期，不代表论文的发表时间）