Spectroscopic investigated to the interaction of human serum albumin with fluorescence carbon nanoparticles

摘要：

　　The interaction of SiO2 including carbon nanoparticles (CNPs) with human serum albumin (HSA) in vitro under simulated physiological conditions has been studied by fluorescence methods and dynamic light scattering (DLS).Experimental results indicated that SiO2 including CNPs can be stabilized in the physiological environment and emit fluorescence,which quench HSA fluorescence by a static quenching mechanism.Our findings indicate that understanding the interaction between proteins and carbon nanoparticles is crucial for toxicological studies.

关键词： SiO2 including CNPs human serum albumin interaction

作者: Fen Jin

作者单位: Hubei Key laboratory of environmental pollution control and reuse,College of Enviromental Science and Engineering,Huangshi Institute of Technology,Huangshi,435003,China;College of Chemistry and Chemical Engineering,Hunan University,Changsha,410082,China

会议类型: 国际会议

会议名称: the international conference on Frontier of Nanoscience and Technology (2011纳米科学与技术国际会议(ICFNST 2011))

会议地点: 大理

会议语种:英文

页码: 396-398

在线出版日期: 2011-08-18（万方平台首次上网日期，不代表论文的发表时间）