Animal experiment of viscose carbon fiber based C/C composites applied in bone fracture intramedullary fixation
The impurity element species and the biological toxic element content of viscose fiber based C/C composites were determined by atomic fluorescence analyzer and inductively coupled plasma atomic emission spectrometry.The results reveal that there are few biological toxic elements in the viscose fiber based C/C composites and it can satisfy the constituent demands of surgical implants.The animal experiment of viscose carbon fiber based C/C composites applied in bone defection intramedullary fixation was carried out in New Zealand white rabbits.The histological observation at 100 day after surgical operation indicated that the experimental animals recovered well and the bone defect area were reconstructed by new bone trabecula.Immunohistochemical observation of leukocyte common antigen and macrophage suggested that intramedullary fixation materials did not induct any chronic toxicity reactions such as inflammatory reactions,macrophage reactions and formation of granulation tissue.The tissue compatibility of this material is excellent.
Viscose carbon fiber bases C/C composites histological observation biocompatibility
Cao Ning Wang Wenbo Dong Jianwen
College of Mechanical and Electronic Engineering, China University of Petroleum, Qingdao 266580, Shandong University of Chinese Traditional Medicine, Jinan 250355
国际会议
上海
英文
168-168
2012-10-19（万方平台首次上网日期，不代表论文的发表时间）