Investigation on local optical parameters of liver tumors in laser-induced thermotherapy
The method to investigation the changes of optical properties and evaluating the effect of laser application in real time is presented in this paper.In vivo measurements of the reduced scattering coefficient (μs) and tissue temperature (T) were performed with a functional near infrared spectroscopy (fNIRS) system and a temperature measurement system during LITT.Mice liver tumors were examined in vivo in different laser doses (0.SW,1.0W,1.2W,1.4W) at a certain heating time (600s).The results showed that there were the same rising tendencies of the reduced scattering coefficient and temperature during LITT.They increased quickly at the beginning,gradually reached a stable state,and rose faster when the laser power was greater.When the tissue temperature was in the range of 50℃ to 70℃,there was a clear linear relationship between μs and T.The linear equation was obtained for the first time.
Laser-induced Thermotherapy functional Near Infrared Spectroscopy Reduced Scattering Coefficient Rat liver tumor Therapy Effect Assessment
Lijuan Dai Guoran Hua Aiping Qian Zhiyu Qian
Department of Mechanical Engineering, Nantong University, Nantong,Jiangsu,226019,China Department of Biomedical Engineering, Nanjing University of Aeronautics and Astronautics,Nanjing, Ji
国际会议
台湾
英文
3998-4002
2011-12-11（万方平台首次上网日期，不代表论文的发表时间）