Fabrication and Biocompatibility of Gradient Bioceramic Coatings on Titanium Alloy Substrate by Laser Cladding

摘要：

　　Based on a high power CO2 laser beam passing by pyramid polygon mirror,the bioceramic coatings of gradient composition were fabricated on titanium alloy substrate (Ti-6Al-4V).The relations among laser processing parameters,microstructure and biocompatibility of the gradient bioceramic coatings were investigated.The results indicated that the contents of rare earth oxide additions had an immediate effect on the formation of bioactive phases.The gradient bioceramic coatings showed favorable biocompatibility in vivo after they were implanted into canine femur for 45,90,and 180 days,respectively.The bioceramic coatings of Ca/P=1.4 and 0.6wt.% Y2O3 totally combined with new bones merely implanted for 45 days.Furthermore,the MTT (Methyl Thiazolyl Tetrazolium) colorimetry results of cell proliferation demonstrated that the cell growth distinctly increased on the gradient bioceramic coatings by laser cladding compared with the un-treated titanium alloy substrate.

关键词： Laser cladding Bioceramic Biocompatibility

作者: Min Zheng Ding Fan Xiu-kun Li Qi-bin Liu Wen-fei Li Jian-bin Zhang

作者单位: State Key Laboratory of Gansu Advanced Non-ferrous Metal Materials,Lanzhou University of Technology, College of Materials Science and Engineering,Guizhou University,Guiyang 550003,China

会议类型: 国际会议

会议名称: The Fifth China International Conference on High-Performance Ceramics (第五届先进陶瓷国际研讨会(CICC-5))

会议地点: 长沙

会议语种:英文

页码: 1203-1205

在线出版日期: 2007-05-10（万方平台首次上网日期，不代表论文的发表时间）