Portable-surface plasmon resonance biosensor immunoassays for the human serum albumin detection

摘要：

　　The screening of urine human serum albumin (HSA) is significant for the early diagnosis and intervention of the nephropathia.This study developed sensitive HSA detection assay with a self-made portable-SPR biosensor based on the reflection light intensity interrogation.Anti-HSA monoclonal antibody was immobilized onto the gold sensing area and a directive assay for HSA was developed.A detection range of 1–100μg/mL HSA was found.The described label-free,real-time immunoassay for the quantification of HSA in urine is a rapid,sensitive,alternative method available for the clinic detection.

关键词： surface plasmon resonance biosensor human serum albumin detection

作者: Hui Li Lu-lu Zhang Hao-yuan Cai Xing Chen Jian-hai Sun Ya-peng Chao Da-fu Cui

作者单位: State Key Lab. of Transducer Tech., Inst. of Electronics,Chinese Academy of Sciences, Beijing, China Institute of Microbiology, Chinese Academy of Sciences, Beijing, China ,100101

会议类型: 国际会议

会议名称: 中国微米纳米技术学会第14届学术年会、第3届国际年会暨第6届微米纳米技术“创新与产业化国际研讨与展览会(CSMNT2012 & ICMAN2012)

会议地点: 杭州

会议语种:英文

页码: 1-5

在线出版日期: 2012-11-04（万方平台首次上网日期，不代表论文的发表时间）