Study on the Preparation of Streptomycin Imprinted Polymers on the Surface of Silica Micro and Nano Spheres
The integration of molecular imprinting technique and solid-phase extraction (SPE) implements an effective alternative for sample pre-concentration in the determination and analysis of veterinary drug/pesticide residues.Herein,we reports a preliminary study on the preparation of streptomycin imprinted polymers on the surface of silica micro-spheres (with an average size of 50μm) and nano-spheres (with an average size of 500nm) via sol gel method.A mixed solution of tetrahydrofuran,ethanol and water (volume ratio is 7:1:1) was choose as dispersion agent,3-aminopropyltriethoxysilane and phenyltriethoxysilane as functional monomers,and tetraethyl orthosilicate as cross-linker,while ammonia solution served as catalyst in the polymerization process.Scanning electron microscopic characterization was employed,suggesting that activating time exerts important influences on the morphology of activated silica micro-spheres,and also resultant molecular imprinted polymers (MIPs).The absorption capacity and selectivity of the obtained two MIPs were also evaluated for streptomycin and its analogue compounds in water samples.The results illustrate that the streptomycin-imprinted silica micro-spheres (MMIP) exhibited both larger absorption capacity and higher selectivity than those of silica nano-spheres (NMIP).The variant analytical performance might result from inadequate polymerization on the surface of silica nano-spheres.
Li Zhifei Li Junjie Huo Danqun Yang Mei Li Xianliang Wang Guomin Fa Huanbao Hou Changjun
College of Bioengineering, Chongqing University, Chongqing, PR China Chongqing Engineering Research Center for Import and Export Food Safety, Chongqing, PRChina College of Chemistry and Chemical Engineering, Chongqing University, Chongqing, PR China
国际会议
中国微米纳米技术学会第14届学术年会、第3届国际年会暨第6届微米纳米技术“创新与产业化国际研讨与展览会(CSMNT2012 & ICMAN2012)
杭州
英文
1-6
2012-11-04（万方平台首次上网日期，不代表论文的发表时间）