Specific rebinding properties of protein imprinted calcium polyacrylate /alginate hybrid microspheres via the adjustment of pH values

摘要：

　　Calcium polyacrylate/alginate (CPA/A) hybrid polymer microspheres with the imprinting of bovine serum albumin (BSA) were prepared via Ca2+ crosslinking of sodium polyacrylate (SPA),BSA and sodium alginate (SA) in inverse suspension.The specific rebinding properties of BSA imprinted hydrogel microspheres (CPA/A MIPMs) were investigated by controlling pH value from the viewpoint of adjusting the process of gelling,removing template and rebinding.The optimized pH values for the imprinting of BSA in gelling,removing template and rebinding process was 4.1,8.3 and 4.2,respectively.

关键词： hybrid hydrogel protein molecular imprinting swelling rebinding pH adjustment

作者: Wenkui Cui Kongyin Zhao Guoxiang Cheng Junfu Wei Li Chen

作者单位: School State Key Laboratory of Hollow Fiber Membrane Materials and Processes, Tianjin Polytechinic U School of Material Science and Engineering, Tianjin University, Tianjin 300072, China School State Key Laboratory of Hollow Fiber Membrane Materials and Processes, TianjinPolytechinic Un

会议类型: 国际会议

会议名称: 中国微米纳米技术学会第14届学术年会、第3届国际年会暨第6届微米纳米技术“创新与产业化国际研讨与展览会(CSMNT2012 & ICMAN2012)

会议地点: 杭州

会议语种:英文

页码: 1-5

在线出版日期: 2012-11-04（万方平台首次上网日期，不代表论文的发表时间）