Preparation of Small-diameter Silk Fibroin Tubular Scaffolds with Electrospinning Method
In recent years,electrospinning has received much attention to prepare porous tubular scaffold due to electrospun nanofibers mat,which can mimic the structure characteristics of the extracellular matrix (ECM).In the present paper,silk fibroin (SF) tubular scaffolds with smalldiameter were prepared by electrospinning from regenerated silk fibroin(RSF)aqueous solutions with rotating mandrel collector.The morphology and fiber diameter distribution of SF tubular scaffolds were influenced much by the concentration of regenerated silk fibroin (RSF) solution,collecting distance and mandrel diameter.The results showed that SF tubular scaffold,which was in flat surface with smaller fiber diameter and uniform distributed,could be obtained at the concentration of 22%,collection distance of 10 cm and mandrel diameter of 4 mm.The structure of SF tubular scaffolds before and after ethanol treatment was characterized by FTIR and XRD.After ethanol treatment,the SF tubular scaffolds had a conformation transition from random-coil conformation to Silk II conformation.
Electrospinning Silk fibroin Tubular scaffolds
Jingxin Zhu Yanlong Ma Tetsuo Asakura
College of Material Science and Engineering, Taiyuan University of Technology,Taiyuan 030024, China Department of Biotechnology, Tokyo University of Agriculture and Technology,Tokyo 184-8588, Japan
国际会议
the Chinese Materials Congress 2012(2012年中国材料大会(CMC2012))
太原
英文
1-5
2012-07-13（万方平台首次上网日期，不代表论文的发表时间）