Effects of Near Infra red Laser for Cultured Bone Marrow Mesenchymal Stem Cells in Different Densities and irradiation periods
Application of chemotherapy drugs,nowadays,is almost necessary for cancer treatment.But,this treatment can suppress the activity of the bones marrow and more importantly is harmful at patients.What’s more,usage of these drugs is limited due to their side effects and cost.Consequently,the following experiment was outlined in which mesenchymal stem cells were cultured.In order to control energy density and waist of beam,appropriate optical set up was designed to investigate the effects of low power near infra red laser with different densities and various irradiation periods on proliferation and citotoxicity of mesenchymal stem cells’ mouse.The result in first experiment showed positive effects of proliferation of the cells,but no sign of cytotoxicity were observed.However in second experience we observed sign of citotoxicity.In some periods,significant proliferation in a dose-dependent manner in comparison with non-irradiated cells was shown.According to this experiment,irradiation of near infra red laser could stimulate proliferation of mesenchymal stem cells that depends on density of power and irradiation periods.
Near infrared laser bone marrow mesenchymal stem cells
V. Farzam Rad E. Safari R. Jafari Jozani S. Jafari Kamangar
Department of Atomic and molecular, Faculty of Physics,Univearsity of Tabriz, Tabriz, Iran Department of clinical science Veterinary, Faculty of veterinary, University of Tabriz, Tabriz, Iran
国际会议
World Congress on Medical Physics and Biomedical Engineering (2012年医学物理及生物医学工程国际会议(IFMBE))
北京
英文
34-37
2012-05-26（万方平台首次上网日期，不代表论文的发表时间）