A follow up MRI-based geometry and computational fluid dynamics study of carotid bifurcation
Cardiovascular disease is the leading causes of death in the developed world.Wall shear stress (WSS) is associated with the initiation and progression of atherogenesis.This study combined the recent advances in MR imaging and computational fluid dynamics (CFD) and evaluated the patient-specific carotid bifurcation.The patient was followed up for 3 years.The geometry changes (tortuosity,curvature,ICA/CCA area ratios,central to the cross-sectional curvature,maximum stenosis) and the CFD factors (Velocity distribute,Wall Shear Stress (WSS) and Oscillatory Shear Index (osI)) were compared at different time points.The carotid stenosis was a slight increase in the central to the cross-sectional curvature,and it was minor and variable curvature changes for carotid centerline.The OSI distribution presents ahigh-values in the same region where carotid stenosis and normal border,indicating complex flow and recirculation.The significant geometric changes observed during the follow-up may also cause significant changes in bifurcation hemodynamics.
Carotid bifurcation shear stress Oscillatory Shear Index (OSI) CFD Stenosis MRL
Yi-Qiang Zeng Zhi-Yong Li
School of Biological Science and Medical Engineering, Southeast University, Nanjing 210096, China
国际会议
World Congress on Medical Physics and Biomedical Engineering (2012年医学物理及生物医学工程国际会议(IFMBE))
北京
英文
172-175
2012-05-26（万方平台首次上网日期，不代表论文的发表时间）