HYPER-GRAVITY AFFECTS ON MORPHOLOGY OF ADIPOSE-DERIVED STEM CELLS

摘要：

　　It has been demonstrated that changes in specific inertial conditions (i.e.microgravity and hyper-gravity) can affect morphology and cytoskeleton.In this report we indicate the effect of hyper-gravity on morphology of Adipose-Derived Stem Cells (ADSCs).ADSCs were repeatedly exposed to discontinues hyper-gravity conditions 10g,20g,40g,60g (three times,each time 20 min with 40 min exposure at 1g between sets) by using centrifuge.Then cell morphology in terms of length,width,angle and CEI (cell elongation index) and cytoskeleton filament actins were analyzed by Image Processing Techniques.After hyper-gravity exposure,significant changes were observed in cell morphology in case of CEI and filament actin shape as a component of cytoskeleton.

关键词： hyper-gravity adipose derived stem cells cell morphology cell elongation cytoskeleton

作者: A. R. TavakoliNejad M. Janmaleki M. Rabbani H. Peirovi M. Marandi

作者单位: Nanomedicine and Tissue Engineering Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran

会议类型: 国际会议

会议名称: World Congress on Medical Physics and Biomedical Engineering (2012年医学物理及生物医学工程国际会议(IFMBE))

会议地点: 北京

会议语种:英文

页码: 203-205

在线出版日期: 2012-05-26（万方平台首次上网日期，不代表论文的发表时间）