Tracking Adaptive Controller Gains to examine the effects of mechanical disturbances to the airway tone in sheep that have asthma-like responses

摘要：

　　An adaptive control model was able to track lung dynamics from sheep that have asthma-like responses.This model can identify airway response during allergen induced bronchoconstriction by adjusting the controller gains for lung resistances.This study examines the rate of adaptation of the controller gains as the airway responses are disturbed by mechanical ventilation.End-tidal CO2 and O2 gasses were also monitored during these disturbances.Mechanical disturbances of the airways can have an immediate and short term relaxing effect on the bronchochonstriction with no apparent changes in end tidal gasses.

关键词： Adaptive Control Lung Resistance End-tidal CO2 end-tidal O2 and Allergen response

作者: E. Koumoundouros K.J. Snibson G. Barcham I.M.Y. Mareels

作者单位: Department of Electrical and Electronic Engineering, The University of Melbourne, Melbourne, Austral Centre of Animal Biotechnology, The University of Melbourne, Melbourne, Australia Department of Electrical and Electronic Engineering, The University of Melbourne, Melbourne, Austral

会议类型: 国际会议

会议名称: World Congress on Medical Physics and Biomedical Engineering (2012年医学物理及生物医学工程国际会议(IFMBE))

会议地点: 北京

会议语种:英文

页码: 418-421

在线出版日期: 2012-05-26（万方平台首次上网日期，不代表论文的发表时间）