Assessment of the Baroreflex in Stroke and Hypertension Patients Using Cross-Correlation Function

摘要：

　　In this study,cross-correlation function (CCF) were applied to assess the correlation between systolic arterial blood pressure and mean heart rate signals acquiring from stroke and hypertension patients both in supine and head-up tilt positions to evaluate the difference of high blood pressure on baroreflex.11 hypertension patients (50.1±10.3 years) and 10 stroke patients (56.0±10.1 years) were included in this study.Mean arterial blood pressure level in these two group did not show significant difference (stroke: supine: 117.99 mmHg; tilt:112.25mmHg,; hypertension: supine:107.04 mmHg; tilt: 105.54mmHg,p>0.05).Results revealed that cardiac-baroreceptor sensitivity (BRS) and α index values in these two groups were not significantly different (p>0.05) during supine and headup tilt positions.However,α index values in stroke and hypertension patients reduced in response to head-up tilt (stroke: supine:10.21; tilt:7.14,p<0.05 ; hypertension: supine:11.25; tilt: 7.52,p<0.05).In the results of CCF analysis,it did not showed significant difference in CCF parameters between these two groups during supine position.However,max CCF index (sec) decreased significantly (p<0.05) in hypertension group during head-up tilt.The decreasing time lag might indicate baroreflex disturbance function.Therefore,baroreflex function might be different between hypertension and stroke patients in response to head-up tilt.On the other hand,max CCF index values were significantly lower (p<0.05) in hypertension group than those in stroke group during head-up tilt position.Due to max CCF index stands for phase lag,phase lag in hypertension was lower than that in stroke group.In conclusion,both stroke and hypertension patients were in high blood pressure,but correlation between blood pressure and hear rate was different.It might be the cause and effect of high blood pressure was different.The results could provide another way to look insight the baroreflex and correlation between blood pressure and heart rate.

关键词： Stroke Hypertension Baroreflex Crosscorrelation function

作者: Ben-Yi Liau Shoou-Jeng Yeh

作者单位: Department of Biomedical Engineering, Hungkuang University, Taichung, Taiwan Section of Neurology and Neurophysiology, Cheng-Ching Hospital, Taichung, Taiwan

会议类型: 国际会议

会议名称: World Congress on Medical Physics and Biomedical Engineering (2012年医学物理及生物医学工程国际会议(IFMBE))

会议地点: 北京

会议语种:英文

页码: 601-603

在线出版日期: 2012-05-26（万方平台首次上网日期，不代表论文的发表时间）