Clinical Observation on the Effects of Different Doses of Tramadol Injection for Preemptive Analgesia in Gynaecological Laparoscopy
Objective: To observe the analgesic effects of tramadol in general anaesthesia for laparoscopic surgery.Methods: To operate eighty laparoscopic surgeries under the circumstance of general anaesthesia.Randomly divide them into 4 groups,with 20 cases in each group and the intravenous injection should be finished before the operation.Group Ⅰ: 2ml normal saline; Group Ⅱ: 1.5ml/kg tramadol; Group Ⅲ: 2mg/kg tramadol; Group Ⅳ: 2.5mg/kg tramadol.Use VAS and Ramsay sedation marking system to assess the degree of pain-feeling and sedation in these circumstances: after pulling out oxygen hose,before leaving the operation room and 1,2,4,8,12,24 hours after the operation.Meanwhile,record such side effects as nausea,vomiting,dizziness,hypersomnia,restless,nightmares,itchy and sweating.Results: The VAS score was significantly lower within postoperative 8 hours in Group Ⅱ,Ⅲ and Ⅳ than that in Group Ⅰ,while no significant difference was found among Group Ⅱ,Ⅲ and Ⅳ at each time point.The postoperative Ramsay sedation score was 0~2 in each group.Incidence of postoperative nausea,vomiting,and sweating were more in Group Ⅱ,Ⅲ and Ⅳ than that in Group Ⅰ.Group Ⅳ and Group Ⅰhave statistical differences,in which P <0.05 or P<0.01.However,Group Ⅱ,Ⅲ and Group Ⅳ have no statistical differences.Conclusion: The study suggests that preoperative injection of 1.5mg/kg~2mg/kg tramadol provides satisfactory preoperative analgesia in patients undergoing gynaecological laparoscopy,reducing the use of analgesics and the incidence of side effects.
gynaecological laparoscopy analgesia general anaesthesia tramadol
Yao Qun Yao Li
Anesthesiology Department, Municipal Hospital, Zaozhuang, China gynecological Department, Municipal Hospital, Zaozhuang, China
国际会议
World Congress on Medical Physics and Biomedical Engineering (2012年医学物理及生物医学工程国际会议(IFMBE))
北京
英文
680-683
2012-05-26（万方平台首次上网日期，不代表论文的发表时间）