Microcirculation imaging with multicolor LEDs and mini CCD camera
The microcirculation is defined as the smallest vessels where gas and nutrient are exchanged with tissues.In treatment of critical care,it is desired to monitor microcirculatory dysfunction to feedback it.The recent development of new imaging modalities such as Sidestream Dark Field (SDF) imaging has helped to directly investigate microcirculation for clinical and experimental studies.In this study,in order to acquire clinically useful information from more sophisticated analysis of the SDF images,we have made a trial model for SDF imaging.Four kinds of LEDs were attached to a miniature CCD camera to acquire images under proper illumination.First,we observed the blood flow in human sublingual microcirculation and pig mucosal microcirculation.We then conducted an experiment on biological phantom to analyze microcirculation of the oxygen saturation.In this paper,we present the principle and the specifications of the trial model as well as some images obtained in the experiments.
Sublingual microcirculation Blood vessels SDF imaging LED Spectral image
Zhenguang Li Saori Kaneko Shigeto Oda Hiroshi Kawahira Hideki Haneishi
Graduate School of Engineering, Chiba University, Chiba, Japan Graduate School of Medicine, Chiba University, Chiba, Japan Research Center for Frontier Medical Engineering, Chiba University, Chiba, Japan
国际会议
World Congress on Medical Physics and Biomedical Engineering (2012年医学物理及生物医学工程国际会议(IFMBE))
北京
英文
1006-1009
2012-05-26（万方平台首次上网日期，不代表论文的发表时间）