The Correlation Study of Ultrasonic Parameters and Youngs Modulus of Cancellous Bone during Decalcification
This study applied a chemical decalcification method to explore the variations of ultrasonic parameters and Young’s modulus of the cancellous bone samples at different decalcification stages and the correlations between them.Cancellous bone specimens were obtained from proximal ends of bovine femoral and then resorted to progressively decalcification with ethylene diamine tetraacetic acid solution.Ultrasonic parameters and young’s modulus were measured and computed based on ultrasonic experiment and mechanical measurement respectively at different decalcification stages,and their correlations were investigated using SPSS software.The results showed that all the parameters including speed of sound,broadband ultrasonic attenuation,amplitude attenuation and Young’s modulus decreased with calcium loss.Strong linear correlations between Young’s modulus and ultrasonic parameters (correlation coefficient r(E,SOS)=0.913,r(E,nBUA)=0.988 and r(E,AA)=0.964) were found.This study may provide some useful information for the detection of osteoporosis with the methods of ultrasonic.
Cancellous bone Ultrasonic Young’s modulus Linear correlations Decalcification
FAN Fan HUANG Chengwu ZHANG Xia NIU Haijun FAN Yubo
Key Laboratory of Ministry of Education for Biomechanics and Mechanobiology, School of Biological Science and Medical Engineering,Beihang University, Beijing 100191, China
国际会议
World Congress on Medical Physics and Biomedical Engineering (2012年医学物理及生物医学工程国际会议(IFMBE))
北京
英文
1097-1100
2012-05-26（万方平台首次上网日期，不代表论文的发表时间）