Effect of head-down human body position on chemoreflex control of breathing

摘要：

　　Modified methods aimed for future studies of chemoreflex control of breathing during long space missions are presented.A study of the control in sitting and head-down supine subjects was performed by these methods.Tidal volume and ventilatory hypercapnic responses were analyzed in PETCO2 range between 45 mmHg and 65 mmHg.Progressive hypercapnic – hypoxic rebreathing revealed posture changes in chemoreflex control,so it is reasonable to use this method in space studies as well as the methods of hyperoxic rebreathing and of isocapnic rebreathing.Chemoreflex control of tidal volume response,i.e.VTR,has a greater sensitivity to posture than ventilation response,i.e.VR,so it is recommended to include tidal volume in the parameters of study in space flights.

关键词： chemoreflex control of breathing tidal volume response ventilatory response sitting upright position supine head-down position

作者: Eugene S. Ermolaev Alexander I. Dyachenko Yury A. Shulagin Alexander O.Goncharov Artem V. Demin

作者单位: State Scientific Center of the Russian Federation - Institute of Biomedical Problems of the Russian State Scientific Center of the Russian Federation - Institute of Biomedical Problems of the Russian State Scientific Center of the Russian Federation - Institute of Biomedical Problems of the Russian Department of Molecular and Biology Physics, Moscow Institute of Physics and Technology(State Univer

会议类型: 国际会议

会议名称: World Congress on Medical Physics and Biomedical Engineering (2012年医学物理及生物医学工程国际会议(IFMBE))

会议地点: 北京

会议语种:英文

页码: 2068-2071

在线出版日期: 2012-05-26（万方平台首次上网日期，不代表论文的发表时间）