Deformities of the Erythrocyte under the Action of a Magnetostatic Field
Studies on anomalies in human erythrocyte as a disease symptom started during the XVIIth century.In the XXth century,Singh & Vatsala reported red corpuscle deformities under the effect of a low potency He-Ne laser and in 1996,E.Purón & A.M.Fontela reported similar deformities under the effect of a non-coherent source of light.The generalized use of the magnetostatic field for several therapies makes it necessary to research the damages this field could cause on the tissues.This paper reveals the results when a 1 cm3 of total blood from presumably healthy persons is submitted to the action of a 300,0 μT and 110,0 mT magnetostatic field measured by a gauss meter with 1 Gs accuracy.In both cases,the magnet was oriented in two directions with respect to the surface of blood: perpendicular and collinear.Samples are collected for different times of irradiation.Then they are spread,fixed and colored as usually.Corpuscles are observed at the clinical microscope,where 400 erythrocytes per visual field are observed under physiological conditions.Pictures are shown for the four deformities (toothed (D),prickled (E),cellular pseudo inclusion (PI) and pile of coins (PM)),and graphs of the amount of deformed red cells.A brief theoretical discussion is carried out using a model where the lipid molecule behaves as a magnetic dipole,generated it by rotation,around its longitudinal axis,at 108 rad/s of the electric charge centers localized in their polar head.Morphological changes of the membrane are probably due to a lipid rearrangement caused by the action of the external field on lipid dipole.Conclusions: a) the magnetostatic field affects to the erythrocyte; b) anomalies depend on the exposure time,on the intensity of the field applied and on its orientation; c) the damage caused to the membrane is irreversible.
Erythrocytes magnetostatic phospholipids membrane deformations
A.M.Fontela E. Purón
Instituto Central de Investigación Digital, calle 202, número 1704, entre 17 y 19, Playa, La Habana, Instituto de Ciencia y Tecnología de Materiales, calle Zapata entre G y Mazón, La Habana, CP 10400,
国际会议
World Congress on Medical Physics and Biomedical Engineering (2012年医学物理及生物医学工程国际会议(IFMBE))
北京
英文
2200-2203
2012-05-26（万方平台首次上网日期，不代表论文的发表时间）