Occurrence of Insecticide Biomarkers of Malathion in Produce and Their Absorption and Excretion in the Rat

摘要：

Malathion is an organophosphorus (OP) insecticide extensively used for agricultural pest control. Malathion diacid (MDA) and monoacid (MMA), dimethylphosphate (DMP), dimethylthiophosphate (DMTP) and dimethyldithiophosphate (DMDTP) are important urine biomarkers of malathion and organophosphorous insecticide exposure. However, these metabolites also are formed in produce. In 129 produce samples from the channels of trade, 127 contained more biomarkers than malathion. Under field conditions in Santa Maria, CA, malathion, MMA and MDA dissipated, while DMP, DMTP and DMDTP increased during a 20 d study period. Mole ratios of Biomarkers/CMalathion+Malaoxon) were always > 1 and increased from Day 4 to Day 23.

关键词： malathion biomarkers dialkylphosphates malathion dicarboxylic acid bioavailability

作者: Li Chen Taifeng Zhao John Ross Helen Vega Robert Krieger Canping Pan

作者单位: Department of Applied Chemistry, College of Science,China Agricultural University, Beijing, China Personal Chemical Exposure Program, Department of Entomology,University of California, Riverside, CA Gem Quality Risk, Inc. , Carmichael, CA, USA

会议类型: 国际会议

会议名称: Proceedings of 4th Internatioanl Symposium on Pesticides and Environmental Safety & 5th Pan Pacific Conference on Pesticide Science & 8th International Workshop on Crop Protection Chemistry and Regulatory Harmonization (四届农药与环境安全会)

会议地点: 北京

会议语种:英文

页码: 119-120

在线出版日期: 2012-09-15（万方平台首次上网日期，不代表论文的发表时间）