The Synthesis and Insecticidal Activity of 6- ( Substituted-phenyl) -quinazolinone Derivatives
Quinazolinone derivatives were described by Nihon Nohyaku. It has been reported that these compounds showed good insecticidal activities for Hemipterous insect pests and lack cross-resistance on insect pests that have developed resistance to one ore more classes of insecticides, including imidacloprid and other neonicotinoids. The substituent at the 6position in the quinazolinone ring plays an important role for the insecticidal activity. Herein, a series of novel-6-( substituted-phenyl )-quinazolinone derivatives 6a-6j were designed and synthesized via suzuki couping reaction. Their structures were identified by nuclear magnetic resonance (NMR), and elemental analyses. The relationship between structure and insecticidal activity was also discussed.
quinazolinone suzuki couping reaction synthesis insecticide Aphis craccivora
Haibo Yu Xuegeng Shi Quantao Liu Yuquan Son Bin Li
State Key Laboratory of the Discovery and Development of Novel Pesticide, Shenyang Research Institute of Chemical Industry Co Ltd
国际会议
北京
英文
301
2012-09-15（万方平台首次上网日期，不代表论文的发表时间）