Design, Synthesis and Bioactivity of Modified Nucleosides as Potential Chitin Synthase Inhibitors

摘要：

Chitin, a linear polysaccharide built up of β, 4linked N-acetylglucosamine (GlcNAc) residues, is the main structural component of the fungal cell wall. As it is absent in invertebrates and plants, chitin could be an ideal target for novel antifungal agents and agricultural fungicides with good selectivity and safety

关键词： chitin design synthesis chitin synthase inhibitors uridine nucleosides

作者: Jiwei Zhang Xinling Yang Lulu Chen Jiajing Feng Qi Chen Qing Yang Yun Ling

作者单位: Department of Applied chemistry, College of Science, China Agricultural University,Beijing 100193, C Department of Bioscience and Biotechnology, Dalian University of Technology, Dalian 116012, China

会议类型: 国际会议

会议名称: Proceedings of 4th Internatioanl Symposium on Pesticides and Environmental Safety & 5th Pan Pacific Conference on Pesticide Science & 8th International Workshop on Crop Protection Chemistry and Regulatory Harmonization (四届农药与环境安全会)

会议地点: 北京

会议语种:英文

页码: 339-340

在线出版日期: 2012-09-15（万方平台首次上网日期，不代表论文的发表时间）