Synthesis of Photoreactive Derivatives of Ivermectin

摘要：

Glutamate-gated chloride channels (GluCls) are transmembrane proteins that mediate fast inhibitory neurotransmission in invertebrate nerves and muscles. GluCls belong to the Cys-loop channel family, which includes y-aminobutyric acid- and acetylcholine-gated ion channels. GluCls are activated by glutamate to enhance chloride permeability of cell membranes, resulting in suppression of cell excitation. As GluCls are found only in invertebrates, they are considered important targets for developing selective insecticide/ parasiticides.

关键词： glutamate-gated chloride channel ivermectin photoreactive derivatives

作者: Toshinori Fuse Izumi Ikeda Mao Yamaguchi Kazuhiko Matsuda Yoshihisa Ozoe

作者单位: Division of Bioscience and Biotechnology, Course of Bioresources Science,United Graduate School of A Division of Bioscience and Biotechnology, Course of Bioresources Science,United Graduate School of A Department of Life Science and Biotechnology, Faculty of Life and Environmental Science, Shimane Uni Department of Applied Biological Chemistry, Faculty of Agriculture, Kinki University, Nara 631-8505,

会议类型: 国际会议

会议名称: Proceedings of 4th Internatioanl Symposium on Pesticides and Environmental Safety & 5th Pan Pacific Conference on Pesticide Science & 8th International Workshop on Crop Protection Chemistry and Regulatory Harmonization (四届农药与环境安全会)

会议地点: 北京

会议语种:英文

页码: 397-398

在线出版日期: 2012-09-15（万方平台首次上网日期，不代表论文的发表时间）