A Novel Pyrethroid Receptor Site on a Mosquito Sodium Channel

摘要：

Currently, pyrethroid insecticides are the most effective control measure in global fight against malaria and other mosquito-borne vector diseases because of their high insecticidal activity and relatively low mammalian toxicity. Pyrethroids exert toxic effect by modifying the gating of voltage-gated sodium channels, which are essential for proper electrical signaling in the nervous system. A major threat to the sustained use of pyrethroids is the global emergence of mosquito resistance to pyrethroids.

关键词： pyrethroid resistance sodium channel knockdown resistance Aedes aegypti pyrethroid insecticides

作者: Yuzhe Du Yoshiko Nomura Zhaonong Hu Gul Satar Boris Zhorov Ke Dong

作者单位: Department of Entomology, Michigan State University, East Lansing, MI 48824, USA Department of Biochemistry and Biomedical Sciences, McMaster University, Canada

会议类型: 国际会议

会议名称: Proceedings of 4th Internatioanl Symposium on Pesticides and Environmental Safety & 5th Pan Pacific Conference on Pesticide Science & 8th International Workshop on Crop Protection Chemistry and Regulatory Harmonization (四届农药与环境安全会)

会议地点: 北京

会议语种:英文

页码: 409

在线出版日期: 2012-09-15（万方平台首次上网日期，不代表论文的发表时间）