An Insecticide-induced Novel Glutathione Transferase in Lepidoptera

摘要：

The glutathione transferase (GST) superfamily is associated with the detoxification of endogenous and exogenous compounds. We found that a GST mRNA that was induced in the fat bodies of a silkworm strain exhibiting diazinon resistance. Phylogenetic analysis of the deduced amino acid sequence indicates that this GST belongs to an unclassified group previously (named bmGSTu). Here, we investigated the enzyme properties of this GST and sought to further characterize this GST, bmGSTu, by solving and refining its crystal structure and identifying its catalytic residues.

关键词： glutathione glutathione transferase Lepidoptera

作者: Kohji Yamamoto

作者单位: Faculty of Agriculture, Kyushu University Graduate School, Fukuoka 812-8581, Japan

会议类型: 国际会议

会议名称: Proceedings of 4th Internatioanl Symposium on Pesticides and Environmental Safety & 5th Pan Pacific Conference on Pesticide Science & 8th International Workshop on Crop Protection Chemistry and Regulatory Harmonization (四届农药与环境安全会)

会议地点: 北京

会议语种:英文

页码: 412

在线出版日期: 2012-09-15（万方平台首次上网日期，不代表论文的发表时间）