Three-dimensional Bone Remodeling Simulation using Topology Optimization
Internal bone architecture, with its unique complex material matrix, has long been studied to determine the underlying principles of its adaptation and “remodeling.Wolff proposed that trabecular bone in the proximal femur functionally adapts to external mechanical loading stimuli, orientating to align with the principal stress trajectories.Wolff had observed the “self-optimizing property of bone and theorized that bone achieves maximum mechanical efficiency with minimal mass: a naturally optimum structure.These hypotheses known as Wolffs Law have been analyzed, critiqued, and refined using clinical, experimental, and analytical means.In the past few decades, computational techniques have been developed that utilize the finite element (FE) method to simulate this “bone remodeling process.This present study utilized design space optimization (DSO), a rigorous mathematical structural optimization technique, in order to determine the global optimum structure of the cancellous bone in the proximal femur.DSO is a specialized topology optimization algorithm that attempts to distribute a finite amount of material into the areas of highest loading to achieve an optimal strength to weight ratio by minimizing the global strain energy (SE).This method has the unique ability to describe the intermediate structural adaptation progress in the time domain and incorporate multi-disciplinary and multi-objective models.The objective of this study is to conduct the first micro-level three-dimensional FE bone remodeling simulation of the proximal femur using DSO topology optimization to address Wolff’s hypothesis of self optimization using proven mathematical theory.
Topology Optimization Bone Remodeling Biomechanics
Il Yong Kim Chris Boyle
Department of Mechanical and Materials Engineering,Queen’s University,Kingston,Ontario,Canada.
国际会议
黄山
英文
1-5
2012-06-18（万方平台首次上网日期，不代表论文的发表时间）