Modeling the Electric Field Effects on Heterogeneous Pinsky-Rinzel Neurons under Ephaptic Transmission
Pinsky-Rinzel (PR) field effect models under ephaptic transmission both in a single neuron and coupling neurons are constructed and studied in this paper. In presence of electric field, the extracellular media have already shown to play a constructive role in neuronal system. Different from the physical synapses, the ephapse is dependent on the conductive property of the extracellular media. Under the ephaptic transmission, the electric field strength, the extracellular media and concentration of extracellular potassium ion has great influence on neuronal firing behavior. In the analysis of heterogeneous coupling neurons, applied the same electric field, the smaller heterogeneity, the stronger synchronicity in coupling neurons and with the concentration of extracellular potassium ion increasing in a certain range, the more synchronous phenomenon is observed. These agree with some epileptic seizure experiments in low calcium solution. It is interesting that for smaller heterogeneous coupling neurons, both the larger negative and positive field may lead to synchronicity and for bigger heterogeneous coupling neurons only the larger negative field can synchronize the neurons.
Ephaptic Transmission Field Effect PR Model Synchronicity
Xile Wei Yinhong Chen Jiang Wang Bin Deng Meili Lu Yanqiu Che
School of Electrical Engineering and Automation, Tianjin University, Tianjin 300072 Tianjin Key Laboratory of Information Sensing & Intelligent Control, School of Automation and Electr
国际会议
The 24th Chinese Control and Decision Conference (第24届中国控制与决策学术年会 2012 CCDC)
太原
英文
1184-1189
2012-05-23（万方平台首次上网日期，不代表论文的发表时间）