A Combined Intermediate Pore Blocking-Cake Filtration Model for Protein Fouling during Microfiltration
Previous studies of protein fouling during microfiltration have shown significant discrepancy between filtrate flux and the classical models. A new mathematical model was developed for microfiltration, which considered not only initial fouling due to pore blocking and fast deposition of the protein aggregates on the membrane surface, but subsequent fouling mainly due to the growth of a cake layer and concentration polarization. The model calculation was shown to be in good agreement with experimental data obtained during the dead-end filtration of bovine serum albumin solutions through PVDF microfiltration membranes. The model describes accurately the rapid flux decline during the early stages of the filtration and the much slower decline of flux at long times. The model eliminates the need to using different blocking mechanism to describe the filtration process, and it is developed from the single mechanism to the combined mechanism. The results provide an important insight into the underlying mechanisms for protein fouling during microfiltration.
microfiltration flux protein fouling model
Dong Wenyue Zhang Xinmiao Wang Zhan Chen Sha Shi Longyue Yang Wentao Zhang Xinmiao
College of Environment and Energy Engineering Beijing University of Technology, BJUT Beijing, China Environmental Protection Research Institute BRICI, SINOPEC Beijing, China
国际会议
三峡
英文
2904-2907
2012-05-18（万方平台首次上网日期，不代表论文的发表时间）